Perioperative medicine & outcomes
Intravenous ferric derisomaltose for preoperative anemia in abdominal surgery
Main finding · Change in Hb from baselineResult — go to the resultMD 1.88 g/dL 95 % CI 1.40–2.36Authors' conclusion
In this preliminary report with limited sample size, our findings suggest that a single preoperative dose of 1000 mg of IV ferric derisomaltose improves hemoglobin levels.
Study context
- Population
- Adults with preoperative iron deficiency anemia (hemoglobin (Hb) ≤ 12 g/dL, and ferritin<30 ng/mL or transferrin saturation < 20 %) scheduled for abdominal surgery
- Participants
- 36 treated patients
- Exposure
- Intravenous (IV) ferric derisomaltose vs Control
- IV ferric derisomaltosen = 36
- Outcome
- Change in Hb from baseline
- Follow-up
- 3-4 weeks after drug administration
Main finding
As reported in the abstract
MD
1.88 g/dL
95 % CI 1.40–2.36
IV ferric derisomaltose vs Control
MD 1.88 g/dL (95 % CI 1.40–2.36)
Observational data: associations, not effects.
Further findings
| Outcome | MD (g/dL) (95 % CI) | |
|---|---|---|
| Change in Hb from baseline, after surgeryvs baseline | 0.67 (0.16–1.17) | |
| −0.500.511.5Difference, g/dL (linear scale) |
| Outcome | OR (95 % CI) | |
|---|---|---|
| In-hospital blood transfusion ratePost-hoc analysis | 1.00 (0.29–3.48) | |
| 0.20.5125Odds ratio (log scale) |
Hb improvement, moderate-to-severe (Hb ≤ 10 g/dL) vs mild pre-infusion anemia (subgroup)
- Significantly superior improvement in Hb with moderate-to-severe vs mild anemia
- P = 0.03
Original publication
Intravenous ferric derisomaltose for preoperative anemia in abdominal surgery. J Clin Anesth. Published 3 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →