Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study
Authors' conclusion
No important difference in intubating conditions was found during rapid sequence induction after the administration of either rocuronium 1.0 mg kg-1 or suxamethonium 1.0 mg kg-1 in patients 80 years or above.
Study context
- Population
- Patients 80 years or above, ASA I–IV, BMI < 35 kg m-1–2, RSI with video laryngoscope intubationall evaluated for primary outcome
- Participants
- 90 patients
- Comparison
- Rocuronium 1.0 mg kg-1 vs suxamethonium 1.0 mg kg-1 during RSI
- Primary endpoint
- Proportion of patients with excellent intubating conditions (Fuchs-Buder scale, blinded investigator)
- Follow-up
- 60 s
Methodological detailsblinded outcome assessment, superiority
- Blinded outcome assessment
- Superiority
Primary result
As reported in the abstract
95% CI −16 to 20; P = 0.82
Further findings
First pass success rate
P = 0.90
Onset time · significantly shorter with suxamethonium
(95% CI 7–57) · P = 0.01
| Outcome | P value |
|---|---|
| Intubating difficulty scale (IDS) score | P = 0.48 |
Intubating difficulty scale (IDS) score
- No difference in IDS score
Safety
Postoperative muscle soreness, hoarseness, sore throat
- No difference between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study. Acta Anaesthesiol Scand. Published 5 February 2025. doi:10.
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