Respiratory failure & ventilation
Invasive mechanical ventilation strategies, adjuvants treatments and adverse events among ICU patients with COVID‐19 in Denmark
Authors' conclusion
Lung protective ventilation and prone positioning were used in many of the Danish ICU patients with COVID-19, but barotrauma, prolonged ventilation and death occurred frequently.
Study context
- Population
- ICU patients with COVID-19 receiving invasive mechanical ventilation in Denmark, 10 March 2020 to 2 April 2021first two waves
- Participants
- 774 patients
- Outcome
- Use of invasive mechanical ventilation core strategies and adjuvant treatments, and occurrence of barotrauma and prolonged ventilation
Methodological detailsnationwide, multicentre, 70% males; median age 69 years, Data retrospectively collected from electronic patient records
- Nationwide
- Multicentre
- 70% males; median age 69 years
- Data retrospectively collected from electronic patient records
Main finding
As reported in the abstract
- Patients never exceeding tidal volumes of 8 mL/kg
- 340 (51.5%)
- Time on ventilator in ICU with tidal volumes under 8 mL/kg, all patients
- 77.6% (IQR 54.5%-96.2%)
- Plateau pressure below 30 cm H2O
- 125 (80.6%) patients
- Prone positioning used
- 44.7% of patients
- Barotrauma in ICU
- 169 of 774 (21.8%)
- Prolonged ventilation in ICU
- 220 (28.4%)
Observational data: associations, not effects.
Further findings
Mortality · 90 days
- Died
- 306 (39.5%)
Original publication
Invasive mechanical ventilation strategies, adjuvants treatments and adverse events among ICU patients with COVID‐19 in Denmark. Acta Anaesthesiol Scand. Published 3 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →