Is General Anesthesia for Peripheral Vascular Surgery Correlated with Impaired Outcome in Patients with Cardiac Comorbidity? A Closer Look into the Nationwide Danish Cohort
Main finding · 1 or more complicationsResult — go to the resultOdds ratio 0.97 95% CI 0.95–0.98Authors' conclusion
RA may be associated with a better outcome than GA after lower extremity vascular surgery in patients with a cardiac comorbidity.
Study context
- Population
- Patients with known cardiac comorbidity (ischemic heart disease, valve disease, pulmonary vascular disease, HF, cardiac arrhythmias) undergoing lower extremity vascular surgery, Danish hospitals, 2005–2017
- Participants
- 6,302 patients
- Exposure
- General anesthesia (GA) vs regional anesthesia (RA)
- Outcome
- 1 or more complications
Methodological detailsnationwide registry, multivariable regression, Data extracted from national registries
- Nationwide registry
- Multivariable regression
- Data extracted from national registries
Main finding
As reported in the abstract
Odds ratio
0.97
95% CI 0.95–0.98
By group
RA vs GA
OR 0.97 (95% CI 0.95–0.98)
Observational data: associations, not effects.
Further findings
30-day mortality · 30 days — GA vs RA · unadjusted
P < 0.001
| Outcome | OR (95% CI) | |
|---|---|---|
| 30-day mortality · 30 daysRA vs GA · adjusted for baseline differences | 0.98 (0.97–0.99) | |
| 0.512Odds ratio (log scale) |
Rate of RA over time
- RA rate in 2005
- 48%
- RA rate in 2017
- 20%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Is General Anesthesia for Peripheral Vascular Surgery Correlated with Impaired Outcome in Patients with Cardiac Comorbidity? A Closer Look into the Nationwide Danish Cohort. J Cardiothorac Vasc Anesth. Published 29 March 2024. doi:10.
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