Regional anesthesia

Is pericapsular nerve group block superior to other regional analgesia techniques following total hip arthroplasty? a systematic review and network meta-analysis

Perioper Med (Lond)Published Systematic review and network meta-analysis of randomised controlled trials

Authors' conclusion

PENGB is more likely to reduce the incidence of quadriceps motor block and PONV in patients undergoing THA, but PENGB + PLAI is superior to other regional analgesia techniques (PLAI, PENGB, fascia iliaca compartment block, and quadratus lumborum block) in improving postoperative pain and shortening the length of hospital stay.

Study context

Population
Patients undergoing total hip arthroplasty (THA)
Participants
766 patients · 11 randomized controlled trials (RCTs)
Comparison
PENG block vs other regional analgesia techniques after THA
Outcome
Resting pain scores
Follow-up
6 h after surgery
Methodological detailsCINeMA risk of bias assessment, sensitivity and subgroup analyses
  • CINeMA risk of bias assessment
  • Sensitivity and subgroup analyses

Pooled result

As reported in the abstract

Postoperative resting and movement pain scores within 24 h · within 24 h
  • Pericapsular nerve group block (PENGB) + periarticular local anesthetic infiltration (PLAI) significantly more effective than other treatments; its SUCRA lowest

Further pooled results

Opioid consumption within 24 h and hospital LOS

PENGB + PLAI ranked best in reducing opioid consumption and hospital LOS

Safety

PENGB had significantly lower incidence of quadriceps motor block and postoperative nausea and vomiting (PONV)

Original publication

Is pericapsular nerve group block superior to other regional analgesia techniques following total hip arthroplasty? a systematic review and network meta-analysis. Perioper Med (Lond). Published 4 October 2024. doi:10.1186/s13741-024-00455-y

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