Less use of rescue morphine when a combined PSP/IPP-block is used for postoperative analgesia in breast cancer surgery: A randomised controlled trial
Authors' conclusion
The use of a combined PSP/IPP-block block before breast cancer surgery reduces the need for postoperative rescue morphine, even when compared with the use of intra-operative morphine.
Study context
- Population
- Women undergoing breast cancer surgery (sector resection or radical mastectomy) under GA, two Swedish hospitals, 2017–2020185 available for follow up
- Participants
- 199 women
- Comparison
- Intervention vs Control
- Interventionn = 92
- Controln = 93reference
- Primary endpoint
- Cumulative IV rescue morphine to reach pain control (VAS <40 mm)
- Follow-up
- First 48 h after surgery
Methodological detailstwo-centre
- Two-centre
Primary result
As reported in the abstract
P = 0.021
Further findings
First measured pain score
P = 0.035
Safety
| Outcome | Intervention | Control | P value |
|---|---|---|---|
| Nausea incidence | 8.7 | 12.9% | P = 0.357 |
- Nausea incidence — No significant difference in the incidence of nausea between the groups
- 8.7 vs. 12.9%
Original publication
Less use of rescue morphine when a combined PSP/IPP-block is used for postoperative analgesia in breast cancer surgery: A randomised controlled trial. Eur J Anaesthesiol. Published 12 January 2023. doi:10.
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