Limited English Proficiency and Sepsis Mortality by Race and Ethnicity
Main findingResult — go to the resultOdds ratio 1.12 95% CI 0.88–1.42Authors' conclusion
In a large diverse academic medical center, LEP had no significant association overall with sepsis mortality. In a subgroup analysis, LEP was associated with increased mortality among individuals identifying as non-Hispanic White.
Study context
- Population
- Hospitalized adults with sepsis (CDC criteria, antibiotics within 24 hours, admitted through the ED), large New England tertiary care center, 2016–2019
- Participants
- 2,709 adults
- Exposure
- Limited English proficiency vs English proficiency
- Limited English proficiency (LEP)n = 327
- English proficiency (EP)n = 2,382reference
- Outcome
- Inpatient mortality
Methodological detailssingle-centre, propensity score adjustment
- Single-centre
- Propensity score adjustment
Main finding
As reported in the abstract
Odds ratio
1.12
95% CI 0.88–1.42
Events by group
LEP vs EP
OR 1.12 (95% CI 0.88–1.42)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Inpatient mortality, non-Hispanic White (subgroup)LEP vs EP | OR 1.76 (95% CI 1.41–2.21) | |
| Inpatient mortality, non-Hispanic White (subgroup)LEP vs EP · adjusted analysis | aOR 1.56 (95% CI 1.02–2.39) | |
| Inpatient mortality, racial and ethnic minority (subgroup)LEP vs EP | OR 0.99 (95% CI 0.63–1.58) | |
| Inpatient mortality, racial and ethnic minority (subgroup)LEP vs EP · adjusted analysis | aOR 0.91 (95% CI 0.56–1.48) | |
| 0.512Ratio (log scale) |
Original publication
Limited English Proficiency and Sepsis Mortality by Race and Ethnicity. JAMA Netw Open. Published 2 January 2024. doi:10. 1001/ jamanetworkopen. 2023. 50373
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