Cardiac arrest & resuscitation

Long-term functional and quality of life outcomes for survivors of asystolic out-of-hospital cardiac arrest

ResuscitationPublished Retrospective cohort study

Authors' conclusion

Among 12-month survivors of EMS-treated asystolic OHCA, good functional recovery was achieved by only one-third of patients, with most survivors experiencing persistent disability and impaired HRQoL.

Study context

Population
Adults with emergency medical services (EMS)-treated asystolic out-of-hospital cardiac arrest (OHCA) (excluding EMS-witnessed arrests), Victorian Ambulance Cardiac Arrest Registry, 2010–202456 completed follow-up
Participants
16,803 adults
Outcome
Functional (GOS-E) and health-related quality-of-life (HRQoL) (EQ-5D, SF-12) outcomes, living arrangements and employment status
Follow-up
12 months
Methodological detailsregistry-based, structured telephone interviews
  • Registry-based
  • Structured telephone interviews

Main finding

As reported in the abstract

Functional and HRQoL outcomes among 12-month survivors
Good functional recovery (Glasgow Outcome Scale-Extended (GOS-E) ≥7), respondents
18 (32.1%)
Vegetative state or severe disability
28 (50.0%)
Living at home without ongoing support
23 (41.1%)
Full health on EQ-5D index
9 (16.1%)
Median EQ-5D index score
0.7 (0.5-0.9)
Mean visual analogue scale (VAS) declined from pre-arrest 70.1 to 58.0
p = 0.003

Observational data: associations, not effects.

Further findings

Survival to discharge

Discharged alive
83 (0.5%)

Mortality after discharge · 12 months

12-month mortality
13.3% (95% CI: 7.6-22.7%)
Alive at 12 months
70 (84.3%)
Completed follow-up
56 (80.0%)

Original publication

Long-term functional and quality of life outcomes for survivors of asystolic out-of-hospital cardiac arrest. Resuscitation. Published 8 June 2026. doi:10.1016/j.resuscitation.2026.111165

Composed by AI from the published abstract and checked against it. How Briefs are made →

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