Cardiac arrest & resuscitation

Long-term major events after hospital discharge for out-of-hospital cardiac arrest

Ann Intensive CarePublished Cohort study

Authors' conclusion

Survivors from OHCA must to be considered at high risk of cardiovascular event occurrence whatever the etiology, mainly during the first year following the cardiac arrest

Study context

Population
OHCA patients discharged alive from three hospitals of the Sudden Death Expertise Center (SDEC) Registry, 2011–2015mean age 57
Participants
306 patients
Outcome
Major event: hospital admission for cardiovascular events or death, whichever came first
Follow-up
During (from hospital discharge)
Methodological detailsregistry-based, three hospitals, consecutive patients, Follow-up data from national health insurance database (SNIIRAM) and national French death registry; censored at first event or December 29th, 2016
  • Registry-based
  • Three hospitals
  • Consecutive patients
  • Follow-up data from national health insurance database (SNIIRAM) and national French death registry; censored at first event or December 29th, 2016

Main finding

As reported in the abstract

Major event · median follow-up 3 years (CV admission) and 6 years (survival)

Patients with a major event

38%

Observational data: associations, not effects.

Secondary outcomes

Factors associated with major event: previous chronic HF

HR (95% CI)
Previous chronic HFIndependently associated1.75 (1.06–2.88)

Factors associated with major event: coronary artery disease

HR (95% CI)
Coronary artery diseaseIndependently associated1.70 (1.11–2.61)

Timing of hospital admission for CV events and death

CV admissions mostly in the first year after OHCA; deaths more linear over the whole period

Other factors

Post-resuscitation myocardial dysfunction, cardiogenic shock and cardiologic cause of cardiac arrest not associated with major event

Original publication

Long-term major events after hospital discharge for out-of-hospital cardiac arrest. Ann Intensive Care. Published 12 September 2024. doi:10.1186/s13613-024-01371-6

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