ICU sedation, delirium & recovery
Long-term mental health change patterns in intensive care unit (ICU) survivors: a four-year comparative follow-up from the SMAP–HoPe study
Authors' conclusion
Mental health disorders in ICU survivors persist for a long term, with the prevalence of depression increasing over 4 years.
Study context
- Population
- ICU survivors from seven Japanese ICUs with mental health assessments (HADS, IES-R) at 1 and 4 years post-ICU dischargeof 319 eligible
- Participants
- 223 survivors
- Exposure
- Mental health prevalence at 4 years vs 1 year post-ICU discharge
- Outcome
- Prevalence of mental health disorders (anxiety, depression, PTSD)
- Follow-up
- 4 years post-ICU discharge
Methodological details4-year follow-up of the SMAP-HoPe study, multicentre, growth mixture modeling
- 4-year follow-up of the SMAP-HoPe study
- Multicentre
- Growth mixture modeling
Main finding
As reported in the abstract
Depression: 1 year vs 4 years
24.7% vs 32.7%
p = 0.021
Anxiety: 1 year vs 4 years
15.3% vs 21.6%
p = 0.049
Post-traumatic stress disorder (PTSD): 1 year vs 4 years
5.1% vs 2.7%
p = 0.549
Observational data: associations, not effects.
Further findings
Moderate-stable depression change pattern, higher vs lower education
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Higher education | 0.25 (0.09–0.68) | P = 0.006 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Change patterns (growth mixture modeling)
- Anxiety: minimal and decreasing, mild and increasing, moderate and stable
- Depression: minimal and stable, mild and increasing, moderate and stable
- PTSD: minimal, mild and moderate symptoms that remained stable
Original publication
Long-term mental health change patterns in ICU survivors: a four-year comparative follow-up from the SMAP–HoPe study. J Intensive Care. Published 28 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →