Cardiac arrest & resuscitation

Low bone mineral density increases the risk of multiple rib and sternal fractures during cardiopulmonary resuscitation

ResuscitationPublished Retrospective cohort study

Authors' conclusion

The study identified a statistically significant correlation between low BMD and a higher number of rib and sternal fractures after CPR. Further, in cases with normal BMD, the use of mechanical CC increased the frequency of rib and sternal fractures.

Study context

Population
Cases referred for medicolegal autopsy who had received antemortem cardiopulmonary resuscitation (CPR)
Exposure
Low bone mineral density (BMD) vs normal BMD; Chest compression (CC) modalities
Outcome
Frequency and number of rib and sternal fractures (fracture count) after CPR
Methodological detailsforensic autopsy population, postmortem CT
  • Forensic autopsy population
  • Postmortem CT

Main finding

As reported in the abstract

Rib and sternal fracture count, by BMD

Fracture count (FC)-ratio

1.3

CI 1.0–1.6

BMD-osteopenia

FC-ratio

1.4

CI 1.0–1.9

BMD-osteoporotic

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
Rib and sternal fractures, by CC modalityBystander 43 % · FC-mean 5.3 (3.1-9.3) · Other CC-modality 76 % · FC-mean 7.2 (5.3-9.7)
Frequency of rib and sternal fractures, normal BMD (subgroup)Manual + Mechanical vs Manual · Fisher's Exact TestManual 63.3 % · Manual + Mechanical 88.0 %0.021
  • Rib and sternal fractures, by CC modality: other CC-modality: at least 76 % and 7.2

Rib and sternal fractures, by CC modality

In general, frequency and number of fractures the same across CC-modalities; tendency towards lowest with bystander CC

Original publication

Low bone mineral density increases the risk of multiple rib and sternal fractures during cardiopulmonary resuscitation. Resuscitation. Published 30 December 2025. doi:10.1016/j.resuscitation.2025.110952

Composed by AI from the published abstract and checked against it. How Briefs are made →

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