Paediatric anaesthesia & critical care
Low-flow oxygen delivery using a nasal cannula for apnoeic oxygenation in children undergoing elective surgery under general anaesthesia: A randomised controlled trial
Authors' conclusion
Apnoeic oxygenation using a nasal cannula was effective in preventing oxygen desaturation during laryngoscopy and intubation in children as compared with those who did not receive apnoeic oxygenation.
Study context
- Population
- Children aged 1 to 6 years undergoing elective surgery under GA with endotracheal intubation; laryngoscopy and intubation by a trainee anaesthesiologist
- Participants
- 120 children
- Comparison
- Apnoeic oxygenation via nasal cannula vs no oxygen
- Primary endpoint
- Lowest SpO2 during laryngoscopy and intubation
Methodological detailsprospective, double-blind, single-centre tertiary care teaching hospital, Tertiary care teaching hospital, January 2020 to September 2021
- Prospective
- Double-blind
- Single-centre tertiary care teaching hospital
- Tertiary care teaching hospital, January 2020 to September 2021
Primary result
As reported in the abstract
Lowest SpO2
P = 0.009
Secondary outcomes
- Control: no fall in SpO2 (P < 0.001)
- 43
- Control: SpO2 fell to 95% (P = 0.004)
- 12
- Control: SpO2 fell to 92 to <95% (P = 0.315)
- 1
- Control: SpO2 fell below 92% (P = 0.038)
- 4
- No fall of SpO2 in any patient in the Apnoeic oxygenation group despite longer apnoea time (P = 0.012)
Safety
- No incidence of bradycardia
Original publication
Low-flow oxygen delivery using a nasal cannula for apnoeic oxygenation in children undergoing elective surgery under general anaesthesia: A randomised controlled trial. Eur J Anaesthesiol Intensive Care. Published 21 September 2023. doi:10. 1097/ ea9. 0000000000000034
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