Perioperative medicine & outcomes
Lower alpha frequency of intraoperative frontal EEG is associated with postoperative delirium: A secondary propensity-matched analysis
Authors' conclusion
Intraoperative slower frontal peak alpha frequency is independently associated with POD after cardiac surgery and may be a simple intraoperative neurophysiological marker of a vulnerable brain for POD.
Study context
- Population
- Cardiac surgical patients328 after propensity score matching (PSM)
- Participants
- 828 patients
- Comparison
- Postoperative delirium (POD) vs non-POD
- PODn = 67
- non-PODn = 261reference
- Primary endpoint
- Intraoperative frontal EEG peak alpha frequency (isoflurane effect-site concentration 0.7 to 0.8)
Methodological detailsretrospective, propensity-score matched
- Retrospective
- Propensity-score matched
Primary result
As reported in the abstract
Mean peak alpha frequency, after matching
P < 0.001
Further findings
| Outcome | non-POD | P value |
|---|---|---|
| Mean peak alpha frequency, before matching | mean 8.9 (SD 1.3) Hz | P < 0.001 |
- Mean peak alpha frequency, before matching: 73 POD, 755 non-POD before PSM
Original publication
Lower alpha frequency of intraoperative frontal EEG is associated with postoperative delirium: A secondary propensity-matched analysis. J Clin Anesth. Published 22 November 2023. doi:10.
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