Cardiothoracic & vascular anesthesia
Intra-operative electroencephalogram frontal alpha-band spectral analysis and postoperative delirium in cardiac surgery: A prospective cohort study
Main finding · Intra-operative frontal α power and PODResult — go to the resultAdjusted odds ratio 0.88 95% CI 0.81–0.96Authors' conclusion
A lower intra-operative frontal α-band power is associated with a higher incidence of POD after cardiac surgery.
Study context
- Population
- Adults undergoing elective cardiac surgery under sevoflurane anaesthesia, university hospital, 15 May 2019 to 15 December 2021
- Participants
- 220 adults
- Exposure
- Delirious vs non-delirious patients
- Deliriousn = 65
- Outcome
- POD (CAM-ICU, Confusion Assessment Method and chart review) predicted by intra-operative frontal EEG α-band activity
Methodological detailssingle-centre, 5-min EEG recorded 30 min after induction; α-band power and peak frequency extracted
- Single-centre
- 5-min EEG recorded 30 min after induction; α-band power and peak frequency extracted
Main finding
Intra-operative frontal α power and POD
Adjusted odds ratio
0.88
95% CI 0.81–0.96
P = 0.007
By group
Delirious
−14.03
mean · SD 4.61 · dB
Non-delirious
−11.59
mean · SD 3.37 · dB
Delirious vs non-delirious patients (intra-operative frontal EEG α-band power)
aOR 0.88 (95% CI 0.81–0.96); P = 0.007
As reported in the abstract
- Postoperative delirium (POD) incidence
- 65 (29.5%) of 220
Observational data: associations, not effects.
Further findings
Age
P < 0.001
| Outcome | Delirious | Non-delirious | P value |
|---|---|---|---|
| Pre-operative cognitive global z score | −0.52 ± 1.14 | 0.21 ± 0.84 | P < 0.001 |
Original publication
Intra-operative electroencephalogram frontal alpha-band spectral analysis and postoperative delirium in cardiac surgery: A prospective cohort study. Eur J Anaesthesiol. Published 8 August 2023. doi:10.
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