Cardiothoracic & vascular anaesthesia
Anesthesia-induced electroencephalogram oscillations and perioperative outcomes in older adults undergoing cardiac surgery
Primary result · Postoperative deliriumResult — go to the resultOdds ratio 0.86 95 % CI 0.78–0.95Authors' conclusion
In this study anesthesia-induced oscillations were associated with postoperative outcomes; however, these were not independently associated with delirium or discharge disposition after considering preoperative cognitive and physical health.
Study context
- Population
- Adults over 60 years admitted from home for elective cardiac surgery with CPBof 394 in MINDDS
- Participants
- 302 participants
- Comparison
- Alpha power during isoflurane GA maintenance
- Primary endpoint
- Postoperative delirium (Confusion Assessment Method)
Methodological detailsprespecified secondary data analysis
- Prespecified secondary data analysis
Primary result
Postoperative delirium
Odds ratio
0.86
95 % CI 0.78–0.95
P = 0.004
Alpha power
OR 0.86 (95 % CI 0.78–0.95); P = 0.004
Per decibel increase, as printed
As reported in the abstract
- Incidence of postoperative delirium
- 11.1 %
- Not significant in adjusted analysis
- 0.92 (ORadj 0.92, 95 % CI: 0.81 to 1.03; P = 0.154)
Secondary outcomes
| Outcome | ORadj (95 % CI) | P value | |
|---|---|---|---|
| 30-day readmissionPer decibel increase | 0.80 (0.71–0.91) | P < 0.001 | |
| 0.512Adjusted odds ratio (log scale) |
Non-home discharge
- Non-home discharge not associated with alpha power
Original publication
Anesthesia-induced electroencephalogram oscillations and perioperative outcomes in older adults undergoing cardiac surgery. J Clin Anesth. Published 7 February 2025. doi:10.
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