Pediatric anesthesia & critical care
Lung-protective ventilation and postoperative pulmonary complications during pulmonary resection in children: A prospective, single-centre, randomised controlled trial
Authors' conclusion
LPV did not decrease the occurrence of PPCs compared to non-protective ventilation.
Study context
- Population
- Children aged < 6 years planned for lung resection for congenital cystic adenomatoid malformation with one-lung ventilation (OLV), single-site tertiary hospital
- Participants
- 142 / 71 / 70 / 72
- Comparison
- Lung-protective ventilation (LPV) vs Control
- LPVn = 142
- Controln = 71reference
- Driving pressuren = 70
- 5 cmH 2 O positive end-expiratory pressure (PEEP)n = 72reference
- Primary endpoint
- Incidence of postoperative pulmonary complications (PPCs)
- Follow-up
- Within 7 days after surgery
Methodological detailsdouble-blind, single-centre
- Double-blind
- Single-centre
Primary result
As reported in the abstract
PPCs, LPV vs control
P = 0.45
Secondary outcomes
| Outcome | Driving pressure | 5 cmH 2 O PEEP | P value |
|---|---|---|---|
| PPCs, driving pressure vs 5 cmH 2 O PEEP · within 7 days after surgery | 15.7% | 18.1% | P = 0.71 |
| Driving pressureDriving pressure vs 5 cmH 2 O PEEP | 15 cmH 2 O | 17 cmH 2 O | P = 0.001 |
Lung compliance, oxygenation, dynamic mechanical power
- Higher lung compliance and oxygenation, lower dynamic component of mechanical power in driving pressure vs 5 cmH 2 O PEEP group
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Lung-protective ventilation and postoperative pulmonary complications during pulmonary resection in children: A prospective, single-centre, randomised controlled trial. Eur J Anaesthesiol. Published 5 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →