Respiratory failure & ventilation
Lung ultrasound findings in acute respiratory distress syndrome (ARDS) based on the 2023 global definition: Characteristics and prognostic value of different lung ultrasound (LUS) scores
Authors' conclusion
Early LUS signs differ significantly between survivors and non-survivors among patients meeting the 2023 ARDS definition. Pleural line abnormalities showed an exploratory association with 28-day mortality, suggesting potential value for bedside risk stratification.This study was registered with the Chinese Clinical Trial Registry (Registration Number:ChiCTR2600117533).
Study context
- Population
- Patients meeting the 2023 global definition of acute respiratory distress syndrome (ARDS) admitted to the ICU/EICU of Ningxia Medical University General Hospital from January to September 2025patients included
- Participants
- 224 patients
- Exposure
- LUS signs (regional/total scores, pleural line abnormalities) collected within 24 h of admission, assessed for prognostic value for 28-day mortality using ROC curve analysis
- Non-survivorsn = 66
- Outcome
- 28-day mortality
- Follow-up
- 28 days
Main finding
As reported in the abstract
28-day mortality rate
29.46%
66/224
Observational data: associations, not effects.
Further findings
Correlation of total LUS aeration score with pleural line abnormalities · within 24 h of admission
- R
- 0.505
- P
- P < 0.001
LUS signs in survivors vs non-survivors · within 24 h of admission
- Survivors showed higher proportions of A-lines and normal pleural lines, while non-survivors had more fused B-lines
Pleural line abnormalities for 28-day mortality (ROC curve analysis)
- AUC
- 0.617
- 95% CI
- 0.550-0.681
- P
- P = 0.008
- Exploratory
- Strongest exploratory association with 28-day mortality
Original publication
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