Malglycemia in the critical care setting. Part III: Temporal patterns, relative potencies, and hospital mortality
Authors' conclusion
Absolute and relative hypoglycemia occurred largely in the first 24 h. Relative to all hypoglycemia, the associated mortality from the seemingly less potent but consistently more prevalent hyperglycemia steadily accumulated with increasing length-of-stay.
Study context
- Population
- Critical care patients
- Participants
- 4,790 patients
- Exposure
- Exposure to hyperglycemia, absolute hypoglycemia and relative hypoglycemia
- Outcome
- Hospital mortality
Methodological detailsrisk-adjusted
- Risk-adjusted
Main finding
As reported in the abstract
Estimate (95% CI)P value
Hyperglycemia
OR 1.0020 per hour(1.0009–1.0031)
P = 0.0004Absolute hypoglycemia
OR 1.0616 per hour(1.0190–1.1061)
P = 0.0043Relative hypoglycemia
OR 1.2813 per excursion(1.0704–1.5338)
P = 0.0069Each row per its own increment, as printed
Observational data: associations, not effects.
Further findings
Relative contribution to mortality, first five days
| Outcome | Hyperglycemia | Absolute hypoglycemia | Relative hypoglycemia |
|---|---|---|---|
| Hypoglycemia exposure in first 24 h | — not stated in the abstract | 7.4% | 6.7% |
— not stated in the abstract
- Daily incidence of hyperglycemia across LOS
- 68-76%
Hypoglycemia exposure in first 24 h
- Decreasing thereafter
Original publication
Malglycemia in the critical care setting. Part III: Temporal patterns, relative potencies, and hospital mortality. J Crit Care. Published 15 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →