Perioperative medicine & outcomes

Measuring patient disability in the peri‐operative period using the WHODAS 2.0 questionnaire: a systematic review

AnaesthesiaPublished Systematic review

Authors' conclusion

The effect of surgical procedures on postoperative disability as measured by WHODAS 2.0 is influenced by the type of surgery. Orthopaedic surgery may decrease disability, whereas cancer surgery may be associated with persistent increases.

Study context

Population
Surgical patients with disability measured by WHODAS 2.0 in the peri-operative period39 studies
Outcome
Difference in WHODAS 2.0 summary score before and after surgery (0% no disability to 100% complete disability)

Pooled result

As reported in the abstract

Change in WHODAS 2.0 disability after surgery

Pre-operative disability range

2% to 61%

Disability increase within 3 months of surgery (21 studies)

1% to 17%

Change between 6 and 12 months

0% to −2%

Further pooled results

Orthopaedic surgery (subgroup) · within 3 months

Pre-operative disability generally high
> 35%
Reduction in disability
10-37%

Cancer surgery (subgroup, n = 12 studies) · within 3 months

Pre-operative disability generally lower
< 20%
Small increases in disability
1-8%

Cardiovascular surgery (subgroup) · 3 months

Pre-operative disability
4% and 17%
Difference in disability
−8% to +3%

Reporting heterogeneity

Thresholds to define disability
3
WHODAS 2.0 endpoints
13
Postoperative time-points
8

Original publication

Measuring patient disability in the peri‐operative period using the WHODAS 2.0 questionnaire: a systematic review. Anaesthesia. Published 24 July 2026. doi:10.1111/anae.70287

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