Measuring the impact of maternal critical care admission on short- and longer-term maternal and birth outcomes

Intensive Care MedPublished Retrospective cohort study

Main finding · 1-year hospital readmissionResult — go to the resultHazard ratio 1.93 95% CI 1.33–2.81

Authors' conclusion

Critical care admission increases the risk of adverse short-term and long-term maternal, pregnancy and neonatal outcomes.

Study context

Population
All women delivering in Scottish hospitals, 01/01/2005–31/12/2018
Participants
762,918 deliveries
Exposure
Intensive care unit (ICU) admission vs no ICU admission during pregnancy/puerperium
  • ICUn = 1,449
Outcome
Hospital readmission
Follow-up
1-year post-hospital discharge
Methodological detailsnational healthcare databases, multivariable Cox and logistic regression
  • National healthcare databases
  • Multivariable Cox and logistic regression

Main finding

1-year hospital readmission · 1 year

Hazard ratio

1.93

95% CI 1.33–2.81

P < 0.001

Events by group

ICU vs Non-ICU
HR 1.93 (95% CI 1.33–2.81); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeEstimateP value
1-year mortalityICU vs No ICU · after confounder adjustmentHR 40.06 (95% CI 24.04–66.76)P < 0.001
StillbirthICU vs No ICU · after confounder adjustmentOR 12.31 (95% CI 7.95,19.08)P < 0.001
Neonatal critical care admissionICU vs No ICU · after confounder adjustmentOR 6.99 (95% CI 5.64,8.67)P < 0.001

Reason for ICU admission and mechanical ventilation (ICU admissions)

PPH
225, 15.5%
Eclampsia/pre-eclampsia
133, 9.2%
Required mechanical ventilation
53.8%

Original publication

Measuring the impact of maternal critical care admission on short- and longer-term maternal and birth outcomes. Intensive Care Med. Published 7 June 2024. doi:10.1007/s00134-024-07417-4

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