Pediatric anesthesia & critical care

Median effective dose of 0.2% ropivacaine for ultrasound-guided median nerve block in young children

Anaesth Crit Care Pain MedPublished Dose-finding study

Authors' conclusion

A single dose of ropivacaine was an effective agent for young children requiring ultrasound-guided lower forearm median nerve block in open surgery for trigger thumb.

Study context

Population
American Society of Anesthesiologists (ASA) I–II children scheduled for elective open trigger thumb repair
Participants
52 children
Comparison
1- to 3-year-olds vs 3- to 6-year-olds
  • 1- to 3-year-oldsn = 28
  • 3- to 6-year-oldsn = 24
Outcome
Effective dose (ED50) of 0.2% ropivacaine for ultrasound-guided lower forearm median nerve block
Methodological detailsDixon's up-and-down method, probit regression
  • Dixon's up-and-down method
  • Probit regression

Main finding

As reported in the abstract

ED50

Further findings

ED95 · probit regression

Safety

No adverse events occurred

Original publication

Median effective dose of 0.2% ropivacaine for ultrasound-guided median nerve block in young children. Anaesth Crit Care Pain Med. Published 17 September 2022. doi:10.1016/j.accpm.2022.101159

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