ICU sedation, delirium & recovery

Mental health sequelae and management in survivors of cardiogenic shock: a nationwide population-based study

Crit CarePublished Nationwide population-based cohort study

Main finding · Primary composite endpointResult — go to the resultAdjusted hazard ratio 1.08 95% CI 1.04–1.13

Authors' conclusion

New-onset mental disorders are common and prognostically significant in survivors of CS.

Study context

Population
Adults admitted to intensive care units (ICUs) for cardiogenic shock (CS) 2012–2022 who survived hospital discharge, without pre-existing psychiatric diagnoses, Koreamedian follow-up 3.5 years
Participants
112,297 adults
Exposure
New-onset mental disorders vs No mental disorder
  • New-onset mental disordersn = 11,166
Outcome
Composite of:
  • All-cause death
  • MI
  • Stroke
  • Coronary revascularization
  • HF hospitalization
Methodological detailsKorean National Health Insurance Service database, time-varying exposure
  • Korean National Health Insurance Service database
  • Time-varying exposure

Main finding

Primary composite endpoint

Adjusted hazard ratio

1.08

95% CI 1.04–1.13

Events by group

New-onset mental disorders

9.9%

11,166

New-onset mental disorders vs No mental disorder
aHR 1.08 (95% CI 1.04–1.13)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaHR (95% CI)
Primary composite endpoint, psychiatric medication initiation vs none (patients with mental disorders)44% reduction · medication as time-varying covariate0.56 (0.53–0.59)
All-cause death, psychiatric medication initiation vs none (patients with mental disorders)49% reduction0.51 (0.48–0.55)

Original publication

Mental health sequelae and management in survivors of cardiogenic shock: a nationwide population-based study. Crit Care. Published 20 January 2026. doi:10.1186/s13054-026-05841-0

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