Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study

Intensive Care MedPublished Retrospective cohort study

Authors' conclusion

Survivors of AMI-CS experience substantial mental health morbidity following discharge. Risk of new mental health diagnoses was comparable between survivors of AMI with and without shock.

Study context

Population
Critically ill adult (≥ 18 years) survivors of AMI-CS admitted to hospital in Ontario, Canada, April 1, 2009 to March 31, 2019135 centers
Exposure
AMI-CS survivors vs AMI survivors without shock
  • AMI-CSn = 7,812
Outcome
New mental health diagnosis after hospital discharge (composite of mood, anxiety, or related disorders; schizophrenia/psychotic disorders; other mental health disorders)
Methodological detailspopulation-based, overlap propensity score-weighted
  • Population-based
  • Overlap propensity score-weighted

Main finding

As reported in the abstract

Hazard ratio

0.99

95% CI 0.94–1.03

By group

AMI-CS

109.6

incidence · 95% CI 105.4–113.9 · per 1,000 person-years

AMI without shock

103.8

incidence · 95% CI 102.5–105.2 · per 1000 person-years

AMI-CS vs AMI without shock
HR 0.99 (95% CI 0.94–1.03)

Observational data: associations, not effects.

Further findings

Factors associated with new mental health diagnoses after AMI-CS

Female sex, pre-existing mental health diagnoses, and discharge to a long-term hospital or rehabilitation institute

Original publication

Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study. Intensive Care Med. Published 2 May 2024. doi:10.1007/s00134-024-07399-3

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