Pediatric anesthesia & critical care
Mepivacaine dosing for spinal anesthesia in pediatric orthopedic surgery: a retrospective chart review
Authors' conclusion
As age and weight increased, a lower dose of mepivacaine per kg was administered for spinal anesthesia.
Study context
- Population
- Patients aged 0–18 receiving mepivacaine spinal anesthesia for orthopedic surgery, 2016 to 2022
- Participants
- 3,627 single-shot mepivacaine spinals
- Outcome
- Clinically used mepivacaine dose (mg/kg) by weight and age
Main finding
As reported in the abstract
Median mepivacaine dosage (mg/kg) by age group
- Dosage in mg/kg decreased by patient age and began to plateau at age 15
- Age range 5 to 18 years
Observational data: associations, not effects.
Further findings
Spinal agent use by age (secondary analysis: bupivacaine, chloroprocaine)
- Bupivacaine most common single-shot spinal agent under age 10; mepivacaine more common after age 10
- Chloroprocaine used in patients older than 8 years
Original publication
Mepivacaine dosing for spinal anesthesia in pediatric orthopedic surgery: a retrospective chart review. Reg Anesth Pain Med. Published 2 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →