Organ support & nutrition

Metabolic complications of citrate anticoagulation in continuous renal replacement therapy (crrt): a delphi consensus on indications, monitoring and management

Crit CarePublished Modified Delphi consensus study

Authors' conclusion

These consensus statements support the use of RCA during CRRT in critically ill patients with impaired citrate metabolism and provide practical guidance for monitoring and management of metabolic complications.

Study context

Population
Critically ill patients receiving continuous renal replacement therapy (CRRT) with regional citrate anticoagulation (RCA), including those with impaired citrate metabolism23 completed all rounds
Participants
29 patients
Outcome
Consensus statements
Methodological detailspredefined protocol, CREDES checklist, three iterative survey rounds, international expert panel
  • Predefined protocol
  • CREDES checklist
  • Three iterative survey rounds
  • International expert panel

Recommendations

As reported in the abstract

Consensus achieved on statements

22

Original publication

Metabolic complications of citrate anticoagulation in continuous renal replacement therapy (crrt): a delphi consensus on indications, monitoring and management. Crit Care. Published 13 May 2026. doi:10.1186/s13054-026-06066-x

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