Microbiological features of drowning-associated pneumonia: a systematic review and meta-analysis
Authors' conclusion
DAP are commonly caused by Gram-negative bacteria, especially Aeromonas sp. which is exclusively isolated following freshwater drowning.
Study context
- Population
- Drowned patients, studies published 01/2000–07/2023
- Participants
- 688 patients · 6 studies
- Comparison
- Freshwater vs Seawater
- Outcome
- Pooled prevalence of drowning-associated pneumonia (DAP)
Methodological detailsretrospective cohort studies included
- Retrospective cohort studies included
Pooled result
As reported in the abstract
Pooled prevalence of DAP
Pooled prevalence of drowning-associated pneumonia (DAP)
39%
95% CI 29–48
Further pooled results
| Outcome | Pooled OR (95% CI) | |
|---|---|---|
| Mortality, DAP vs no DAPBased on two studies only | 1.43 (0.56–3.67) | |
| 0.20.5125Pooled odds ratio (log scale) |
Aeromonas sp. by water type (subgroup) · 19/106 in freshwater
P = 0.001
Pooled prevalence
| Outcome | Freshwater | Seawater |
|---|---|---|
| Pooled prevalence of DAP by water type (subgroup) | 44% (95% CI 36–52) | 42% (95% CI 32–53) |
- Mortality, DAP vs no DAP — Mortality range across studies
- 18 to 81%
Microorganisms isolated from respiratory samples
- Microorganisms isolated
- 171
- Gram negative
- 98/171, 57%
- Aeromonas sp.
- 20/171, 12%
- Gram positive
- 38/171 (22%)
- Staphylococcus aureus
- 21/171, 12%
Antimicrobial resistance
- Isolates resistant to amoxicillin-clavulanate (most common empirical drug)
- nearly 30%
- No studies reported multidrug-resistant organisms
Original publication
Microbiological features of drowning-associated pneumonia: a systematic review and meta-analysis. Ann Intensive Care. Published 20 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →