Cardiac arrest & resuscitation
Mild therapeutic hypothermia after cardiac arrest – effect on survival with good neurological outcome outside of randomised controlled trials: A registry-based analysis
Main findingResult — go to the resultOdds ratio 1.60 95% CI 1.49–1.72Authors' conclusion
Our data indicate the existence of a positive association between MTH and a favourable neurological outcome after cardiac arrest.
Study context
- Population
- Adults with OHCA or IHCA, comatose on admission, German Resuscitation Registry (Germany and Austria), 2006–2022analysed
- Participants
- 33,933 adults
- Exposure
- Mild therapeutic hypothermia (MTH) vs no MTH after cardiac arrest
- MTHn = 10,034
- Without MTHn = 23,899reference
- Outcome
- Hospital discharge with good neurological outcome (cerebral performance categories (CPC) 1 or 2)
Methodological detailsmultivariate binary logistic regression, registry
- Multivariate binary logistic regression
- Registry
Main finding
As reported in the abstract
Odds ratio
1.60
95% CI 1.49–1.72
P < 0.001
MTH vs Without MTH
OR 1.60 (95% CI 1.49–1.72); P < 0.001
Observational data: associations, not effects.
Secondary outcomes
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Hospital dischargeMultivariate regression | 1.89 (1.76–2.02) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
Original publication
Mild therapeutic hypothermia after cardiac arrest – effect on survival with good neurological outcome outside of randomised controlled trials: A registry-based analysis. Eur J Anaesthesiol. Published 27 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →