Perioperative medicine & outcomes

Mixed-methods Analysis of Preoperative Distress and Postoperative Outcomes in a Prospective, Observational Cohort of Older Adults

AnesthesiologyPublished Secondary analysis of a prospective observational cohort study

Authors' conclusion

Psychological distress is common among geriatric surgery patients, and higher preoperative stressor count was associated with worse postoperative outcomes.

Study context

Population
Patients aged 65 yr and older undergoing nonintracranial, noncardiac surgery129 engaged in distress assessment
Participants
132 patients
Methodological detailssingle-centre, mixed-methods
  • Single-centre
  • Mixed-methods

Primary result

As reported in the abstract

Preoperative distress (modified NCCN Distress Thermometer) and associations with postoperative outcomes
High distress intensity (≥4 of 10)
42.2%
Stressor count, median [Q1, Q3]
2 [1, 5]
Stressor count vs postoperative hospital LOS, Spearman's r s [95% CI]
0.24 [0.06 to 0.40]; P = 0.017
Stressor count vs postoperative pain, r s [95% CI]
0.25 [0.07 to 0.41]; P = 0.016
Stressor count vs risk for postoperative delirium, OR [95% CI]
1.19 [1.06 to 1.33]; P = 0.009

Further findings

Distress themes (qualitative)

Stressors most associated with high distress: changes in eating, communication with the healthcare team, sleep, worry or anxiety; potentially addressable

Original publication

Mixed-methods Analysis of Preoperative Distress and Postoperative Outcomes in a Prospective, Observational Cohort of Older Adults. Anesthesiology. Published 3 October 2025. doi:10.1097/aln.0000000000005780

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