Anaesthetic drugs & techniques
Sugammadex for preventIoN oF pOst-operative pulmoNary complIcAtions (SINFONIA): protocol for an embedded mixed-methods process evaluation
Study context
- Population
- Patients undergoing major abdominal or thoracic surgery (SINFONIA trial sites)
- Planned comparison
- Sugammadex vs neostigmine to reverse NMB
Methodological detailsexplanatory sequential design, POETIC framework, logic model, electronic survey and semi-structured interviews, multi-centre, pragmatic, Examines Context, Fidelity, Dose, Reach, and Quality of Delivery; quantitative data on intervention delivery first, then qualitative data explaining variation; findings integrated with main trial results
- Explanatory sequential design
- POETIC framework
- Logic model
- Electronic survey and semi-structured interviews
- Multi-centre
- Pragmatic
- Examines Context, Fidelity, Dose, Reach, and Quality of Delivery; quantitative data on intervention delivery first, then qualitative data explaining variation; findings integrated with main trial results
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Sugammadex for preventIoN oF pOst-operative pulmoNary complIcAtions (SINFONIA): protocol for an embedded mixed-methods process evaluation. BJA Open. Published 2 September 2026. doi:10.
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