Moderate factor XI deficiency and neuraxial procedures in an obstetric cohort: a retrospective study (2014–2021)
Authors' conclusion
Our findings are consistent with previous reports of positive outcomes after neuraxial procedures in pregnant women with FXI level >0.30 IU/mL, with a thorough review of personal and family bleeding history.
Study context
- Population
- Pregnant women with Factor XI (FXI) levels ≤0.50 IU/mL admitted to two high-risk obstetric departments, 2014–2021
- Participants
- 101 women · 107 deliveries
- Outcome
- Hemorrhagic complications related to neuraxial anesthesia
Methodological detailstwo-centre
- Two-centre
Main finding
As reported in the abstract
Delivered with neuraxial labor analgesia or cesarean anesthesia
67
Bleeding history among neuraxial patients
9 of 67
13%
Observational data: associations, not effects.
Original publication
Moderate factor XI deficiency and neuraxial procedures in an obstetric cohort: a retrospective study (2014–2021). Int J Obstet Anesth. Published 28 October 2024. doi:10. 1016/ j. ijoa. 2024. 104289
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