Obstetric anesthesia

Moderate factor XI deficiency and neuraxial procedures in an obstetric cohort: a retrospective study (2014–2021)

Int J Obstet AnesthPublished Retrospective cohort study

Authors' conclusion

Our findings are consistent with previous reports of positive outcomes after neuraxial procedures in pregnant women with FXI level >0.30 IU/mL, with a thorough review of personal and family bleeding history.

Study context

Population
Pregnant women with Factor XI (FXI) levels ≤0.50 IU/mL admitted to two high-risk obstetric departments, 2014–2021
Participants
101 women · 107 deliveries
Outcome
Hemorrhagic complications related to neuraxial anesthesia
Methodological detailstwo-centre
  • Two-centre

Main finding

As reported in the abstract

Delivered with neuraxial labor analgesia or cesarean anesthesia

67

Bleeding history among neuraxial patients

9 of 67

13%

Observational data: associations, not effects.

Original publication

Moderate factor XI deficiency and neuraxial procedures in an obstetric cohort: a retrospective study (2014–2021). Int J Obstet Anesth. Published 28 October 2024. doi:10.1016/j.ijoa.2024.104289

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