Perioperative medicine & outcomes
Mortality following noncardiac surgery assessed by the Saint Louis University Score (SLUScore) for hypotension: a retrospective observational cohort study
Authors' conclusion
The SLUScore was independently, but variably, associated with 30-day mortality after noncardiac surgery.
Study context
- Population
- Noncardiac surgical cases, January 1, 2010 to December 31, 2020cases analysed
- Participants
- 490,982 cases
- Exposure
- Intraoperative hypotension
- Outcome
- 30-day mortality by SLUScore (binary logistic regression)
- Follow-up
- 30 days
Main finding
As reported in the abstract
Increase in OR for death within 30 days per SLUScore increment
- All surgery types
- 3.5% (95% CI 3.2-3.9)
- Abdominal/transplant surgery
- 6% (95% CI 1.5-10.7)
- Thoracic surgery
- 1.5% (95% CI 1-3.3)
- Vascular surgery
- 3.01% (95% CI 1.9-4.05)
- Spine/neurosurgery
- 1.1% (95% CI 0.1-2.1)
- Orthopaedic surgery
- 1.4% (95% CI 0.7-2.2)
- Gynaecological surgery
- 6.3% (95% CI 2.5-10.1)
- Genitourinary surgery
- 4.84% (95% CI 3.5-6.15)
- Gastrointestinal surgery
- 5.2% (95% CI 3.9-6.4)
- Gastroendoscopy
- 5.5% (95% CI 4.4-6.7)
- General surgery
- 6.3% (95% CI 5.5-7.1)
- Ear, nose, and throat surgery
- 1.6% (95% CI 0-3.27)
- Cardiac electrophysiology (incl. pacemaker procedures)
- 6.6% (95% CI 1.1-12.4)
Observational data: associations, not effects.
Further findings
Prevalence and severity of intraoperative hypotension
- Cases with SLUScore>0
- 33.2%
- Median SLUScore (IQR 7-21)
- 13
- Average mortality
- 1.19%
Original publication
Mortality following noncardiac surgery assessed by the Saint Louis University Score (SLUScore) for hypotension: a retrospective observational cohort study. Br J Anaesth. Published 3 May 2024. doi:10. 1016/ j. bja. 2024. 03. 039
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