Perioperative medicine & outcomes

Mortality following noncardiac surgery assessed by the Saint Louis University Score (SLUScore) for hypotension: a retrospective observational cohort study

Br J AnaesthPublished Retrospective observational cohort study

Authors' conclusion

The SLUScore was independently, but variably, associated with 30-day mortality after noncardiac surgery.

Study context

Population
Noncardiac surgical cases, January 1, 2010 to December 31, 2020cases analysed
Participants
490,982 cases
Exposure
Intraoperative hypotension
Outcome
30-day mortality by SLUScore (binary logistic regression)
Follow-up
30 days

Main finding

As reported in the abstract

Increase in OR for death within 30 days per SLUScore increment
All surgery types
3.5% (95% CI 3.2-3.9)
Abdominal/transplant surgery
6% (95% CI 1.5-10.7)
Thoracic surgery
1.5% (95% CI 1-3.3)
Vascular surgery
3.01% (95% CI 1.9-4.05)
Spine/neurosurgery
1.1% (95% CI 0.1-2.1)
Orthopaedic surgery
1.4% (95% CI 0.7-2.2)
Gynaecological surgery
6.3% (95% CI 2.5-10.1)
Genitourinary surgery
4.84% (95% CI 3.5-6.15)
Gastrointestinal surgery
5.2% (95% CI 3.9-6.4)
Gastroendoscopy
5.5% (95% CI 4.4-6.7)
General surgery
6.3% (95% CI 5.5-7.1)
Ear, nose, and throat surgery
1.6% (95% CI 0-3.27)
Cardiac electrophysiology (incl. pacemaker procedures)
6.6% (95% CI 1.1-12.4)

Observational data: associations, not effects.

Further findings

Prevalence and severity of intraoperative hypotension

Cases with SLUScore>0
33.2%
Median SLUScore (IQR 7-21)
13
Average mortality
1.19%

Original publication

Mortality following noncardiac surgery assessed by the Saint Louis University Score (SLUScore) for hypotension: a retrospective observational cohort study. Br J Anaesth. Published 3 May 2024. doi:10.1016/j.bja.2024.03.039

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