Multicenter Prospective Randomized Comparison of Ultrasound-Guided Stellate Ganglion Versus Thoracic Paravertebral Block for Sympathetic Blockade in Chronic Upper Extremity Pain
Primary resultResult — go to the resultDifference in success rates 24.6 % 95% CI −9.0% to 58.2%Authors' conclusion
US-guided TPVB had a higher success rate of upper extremity sympathetic blockade than US-guided SGB, with more pronounced immediate postprocedural pain relief.
Study context
- Population
- Patients aged 19 to 85 years with chronic upper extremity pain (complex regional pain syndrome and neuropathic pain)
- Participants
- 35 vs 34
- Comparison
- Ultrasound (US)-guided thoracic paravertebral block (TPVB) vs US-guided stellate ganglion block (SGB)
- TPVBn = 35
- SGBn = 34reference
- Primary endpoint
- Success rate of sympathetic blockade (ΔT difference between affected and unaffected hands ≥ 1.5°C)
- Follow-up
- 20 minutes
Methodological detailsprospective, multicentre
- Prospective
- Multicentre
Primary result
As reported in the abstract
Difference in success rates
24.6 %
95% CI −9.0% to 58.2%
P = 0.041
Events by treatment group
TPVB vs SGB
difference in success rates 24.6 % (95% CI −9.0% to 58.2%); P = 0.041
Secondary outcomes
| Outcome | TPVB | SGB | P value |
|---|---|---|---|
| ΔT difference · 20 minutes | 2.0 ± 1.5 °C | 1.1 ± 1.3 °C | P = 0.008 |
| Pain intensity (11-point NRS) · 20 minutes | 4.3 ± 2.2 | 5.4 ± 2.4 | P = 0.038 |
- Pain intensity (11-point numerical rating scale (NRS)) — Pain decreased in both groups vs baseline
- P < .001
Peak systolic velocity, ipsilateral brachial artery · 20 minutes
- Increased in TPVB
- P = 0.005
- Not observed in SGB
- P = 0.325
Pain intensity (11-point NRS) · 1 week and 4 weeks
- Increased to preintervention levels in both groups
Original publication
Multicenter Prospective Randomized Comparison of Ultrasound-Guided Stellate Ganglion Versus Thoracic Paravertebral Block for Sympathetic Blockade in Chronic Upper Extremity Pain. Anesth Analg. Published 25 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →