Pediatric anesthesia & critical care
Effect of General Anesthesia Combined with Single-Shot, Single-Level Thoracic Paravertebral Block on Postoperative Analgesia in Children Undergoing Thoracoscopic Mediastinal Tumor Resection: A Randomized Controlled Trial
Primary result · AUC-FLACCResult — go to the resultMean difference −11.8 95% CI −14.2 to −9.34Authors' conclusion
Single-shot, single-level TPVB provides early postoperative analgesia in pediatric thoracoscopic mediastinal tumor surgery, enhances short-term recovery, reduces opioid requirements, and does not increase hospital costs or adverse events.
Study context
- Population
- Children aged 4 to 12 years scheduled for thoracoscopic mediastinal tumor resection
- Participants
- 50 vs 51
- Comparison
- GA plus preincision ultrasound-guided thoracic paravertebral block (TPVB) vs GA alone
- Gn = 50reference
- Tn = 51
- Primary endpoint
- Pain intensity, AUC of Face, Legs, Activity, Cry, and Consolability (FLACC) scores (AUC-FLACC)
- Follow-up
- First 24 hours
Methodological detailsprospective, single-centre
- Prospective
- Single-centre
Primary result
AUC-FLACC
Mean difference
−11.8
95% CI −14.2 to −9.34
P < 0.001
By group
T
41.3/240
G
53.0/240
T vs G
mean difference −11.8 (95% CI −14.2 to −9.34); P < 0.001
As reported in the abstract
Secondary outcomes
Pain scores · first 20 hours
- Lower in group T
Questionnaire (QoR-15) scores · 24 hours
- Higher in group T
Intraoperative anesthetic use, postoperative rescue opioids, hospital stay
- All reduced in group T
Original publication
Effect of General Anesthesia Combined with Single-Shot, Single-Level Thoracic Paravertebral Block on Postoperative Analgesia in Children Undergoing Thoracoscopic Mediastinal Tumor Resection: A Randomized Controlled Trial. J Cardiothorac Vasc Anesth. Published 15 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →