Pediatric anesthesia & critical care
Effects of Thoracic Paravertebral Block on Postoperative Analgesia in Infants and Small Children undergoing Ultra-Fast Track Cardiac Anesthesia: A Randomized Controlled Trial
Authors' conclusion
A combination of bilateral single dose TPVB and PNCA pain management is superior to a PNCA pain management alone in infants and small children undergoing open cardiac surgery and contributes to a rapid recovery with preferable perioperative outcomes in the protocol of UFTCA.
Study context
- Population
- Children aged 1 month to 3 years undergoing open cardiac surgery with ultra-fast track cardiac anesthesia (UFTCA), tertiary children's medical center
- Participants
- 180 children
- Comparison
- Preoperative bilateral thoracic paravertebral block (TPVB) plus PNCA vs PNCA alone
- Primary endpoint
- Postoperative pain scores
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
within 24 hours
- Pain scores within 24 h significantly lower in Group T vs Group P
- Group T vs Group P: P < 0.001
Secondary outcomes
| Outcome | P value |
|---|---|
| Intraop sufentanil consumption; total and invalid PCA attempts at 24 and 48 h; perioperative blood glucose; BNP on the seventh daySignificantly lower in Group T | P < 0.001 |
| Time to extubation; use of neostigmine; PaCO2 on the sixth hour postopSignificantly smaller in Group T | P < 0.05 |
Intraop sufentanil consumption; total and invalid PCA attempts at 24 and 48 h; perioperative blood glucose; Brain natriuretic peptide (BNP) on the seventh day
- Significantly lower in Group T than in Group P
Time to extubation; use of neostigmine; PaCO2 on the sixth hour postop
- Significantly smaller in Group T than in Group P
Hospitalization characteristics
- No significant differences between the 2 groups
Original publication
Effects of Thoracic Paravertebral Block on Postoperative Analgesia in Infants and Small Children undergoing Ultra-Fast Track Cardiac Anesthesia: A Randomized Controlled Trial. J Cardiothorac Vasc Anesth. Published 11 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →