Cardiac arrest & resuscitation
Multicentric validation of a prognostic tool for predicting brain death following out-of-hospital cardiac arrest in children
Authors' conclusion
The BDCA score shows promise in children ≥ 12mo following OHCA and may be considered in conjunction with existing multimodal prognostication approaches.
Study context
- Population
- Pediatric patients admitted to PICUs after out-of-hospital cardiac arrest (OHCA) (2011–2021) who survived ≥24 hours but died as a result of their OHCA389 identified
- Participants
- 282 patients
- Exposure
- BDCA score for predicting brain death, children ≥12 mo vs infants <12 mo
- Outcome
- Discrimination of the BDCA score (AUC) for brain death
Methodological detailsmulticentre, 5 PICUs
- Multicentre
- 5 PICUs
Main finding
As reported in the abstract
Discrimination for brain death (AUC)
| Strategy | AUC |
|---|---|
| Age ≥ 12mo | 0.82 [95% CI 0.75, 0.90] |
| Infants < 12mo | 0.61 |
AUC
Age ≥ 12mo0.82 [95% CI 0.75, 0.90]
Infants < 12mo0.61
Observational data: associations, not effects.
Further findings
Brain death outcomes
- Formally declared brain dead
- 169 (59.9%)
- Findings consistent with brain death but withdrawal of life sustaining therapy (WLST) before formal declaration
- 58 (20.6%)
Original publication
Multicentric validation of a prognostic tool for predicting brain death following out-of-hospital cardiac arrest in children. Resuscitation. Published 9 February 2023. doi:10.
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