Hemodynamics, fluids & transfusion

Multimodal Noninvasive Monitoring of Arterial Pressure: Do Limitations of Finger Cuff Monitoring Compromise Upper Arm Measurements? A Post Hoc Analysis of Two Prospective Cohorts

Crit Care MedPublished Post hoc analysis of two prospective observational cohorts

Authors' conclusion

When unreliable or unavailable, cuff ARM provides reliable measurements, effectively detects hypotension and hypertension, and poses no significant risk to the patient.

Study context

Population
ICU adults with an arterial catheter and stable arterial pressure (AP)214 CNAP, 138 ClearSight
Participants
352 adults
Comparison
Oscillometric upper arm cuff (cuffARM) vs finger cuff (cuffFINGER: CNAP, ClearSight), arterial catheter as reference
Methodological detailsthree ICUs, reference: arterial catheter
  • Three ICUs
  • Reference: arterial catheter

Primary result

As reported in the abstract

Mean AP reliability in patients with poor fingertip perfusion (capillary refill time >4 s) and/or hand edema (n = 102, 29%)
GroupValueMeasurements (n)No or low risk of harmAUC hypotension (95% CI 0.87-0.94)AUC hypertension (95% CI 0.75-1)
Cuffbias 2.2 (SD 7.2) mm Hg30499.7%0.910.92
Cuff FINGER17%

Value

Cuffbias 2.2 (SD 7.2) mm Hg
Cuff FINGER17%

Measurements (n)

Cuff304
Cuff FINGER— not stated in the abstract

No or low risk of harm

Cuff99.7%
Cuff FINGER— not stated in the abstract

AUC hypotension (95% CI 0.87-0.94)

Cuff0.91
Cuff FINGER— not stated in the abstract

AUC hypertension (95% CI 0.75-1)

Cuff0.92
Cuff FINGER— not stated in the abstract

Further findings

Mean AP reliability of cuff ARM when cuff FINGER failed to display AP (38 of 352 patients, 11%) — cuff
bias 1.7 (SD 7.1) mm Hg

Mean AP reliability of cuff ARM when cuff FINGER failed to display AP (38 of 352 patients, 11%)

Cuff ARM met ISO 81060-2:2018 standard for mean AP

Mean AP without failure or risk factors for erroneous measurements

ClearSight met ISO 81060-2:2018 standard for mean AP, unlike the CNAP system

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Multimodal Noninvasive Monitoring of Arterial Pressure: Do Limitations of Finger Cuff Monitoring Compromise Upper Arm Measurements? A Post Hoc Analysis of Two Prospective Cohorts. Crit Care Med. Published 14 August 2025. doi:10.1097/ccm.0000000000006841

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