Cardiac arrest & resuscitation
Myoclonus After Cardiac Arrest: Need for Standardization—A Systematic Review and Research Proposal on Terminology
Authors' conclusion
Heterogeneity in definitions resulted in weak associations with outcomes.
Study context
- Population
- Adults (≥ 18 yr) with myoclonus ≤72 hours after cardiac arrest119 studies
- Participants
- 2,659 / 883 / 569 / 40
- Comparison
- Myoclonus vs MyS/SM vs myoclonic status epilepticus (MSE) vs early Lance-Adams Syndrome (eLAS)
- Myoclonusn = 2,659
- MyS/SMn = 883
- MSEn = 569
- eLASn = 40
- Outcome
- CPC 1-2 (among patients with a defined outcome)
Methodological detailsresearch proposal on terminology, PubMed, Embase and Cochrane, 1966 to May 31, 2024; English-language adult studies, Quality: Newcastle-Ottawa Scale and Cochrane Risk-of-Bias tool
- Research proposal on terminology
- PubMed, Embase and Cochrane, 1966 to May 31, 2024; English-language adult studies
- Quality: Newcastle-Ottawa Scale and Cochrane Risk-of-Bias tool
Pooled result
As reported in the abstract
Further pooled results
EEG recorded
- Patients with EEG recorded
- 2714 (69.9%)
Cerebral Performance Category (CPC) 1-2 by EEG pattern
- Suppression/suppression/suppression burst (SB)/unreactive EEG
- 1.6%
- Non-SB/U EEG with SE
- 11.3%
- Non-SB/U EEG without SE
- 22.3%
Original publication
Myoclonus After Cardiac Arrest: Need for Standardization—A Systematic Review and Research Proposal on Terminology. Crit Care Med. Published 22 November 2024. doi:10.
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