Trauma & major bleeding

Narrative Review: Is There a Transfusion Cutoff Value After Which Nonsurvivability Is Inevitable in Trauma Patients Receiving Ultramassive Transfusion?

Anesth AnalgPublished Narrative review

Authors' conclusion

The data examining the utility of UMT in trauma are of poor quality, and with the variability inherent in trauma patients, and the surgeons caring for them, no universally accepted cutoff for transfusion exists.

Study context

Population
Adult trauma patients receiving ultramassive transfusion (UMT)14 studies
Outcome
Effects of UMT on outcomes including survival; whether a threshold transfusion limit exists after which mortality is inevitable

Main finding

As reported in the abstract

  • Data on utility of UMT in trauma of poor quality; no universally accepted transfusion cutoff exists
  • Trend toward increasing mortality with increasing transfusions

Original publication

Narrative Review: Is There a Transfusion Cutoff Value After Which Nonsurvivability Is Inevitable in Trauma Patients Receiving Ultramassive Transfusion? Anesth Analg. Published 28 April 2023. doi:10.1213/ane.0000000000006504

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