Pediatric anesthesia & critical care
Neurodevelopmental impact of prenatal regional or general anaesthesia: An ambidirectional pilot cohort study
Authors' conclusion
No difference in BRIEF scores was observed.
Study context
- Population
- Children born 2011–2018 at Caen Normandy University Hospital, without diagnosed neurodevelopmental disorder6.3–10.3 years old
- Participants
- 94 children
- Exposure
- Prenatal general anaesthesia (GA) or regional anaesthesia (RA) for non-obstetric surgery vs no surgery during pregnancy
- GAn = 40
- RAn = 13
- Controln = 41reference
- Outcome
- BRIEF scores
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- No difference in Behaviour Rating Inventory of Executive Function (BRIEF) scores among the groups
Observational data: associations, not effects.
Further findings
Influence of confounding factors on BRIEF scores
- No confounding factors influenced this result
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Neurodevelopmental impact of prenatal regional or general anaesthesia: An ambidirectional pilot cohort study. Anaesth Crit Care Pain Med. Published 9 July 2025. doi:10.
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