Cardiac arrest & resuscitation

Neurologic Recovery at Discharge and Long-Term Survival After Cardiac Arrest

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

In this cohort study of patients with cardiac arrest who survived beyond 30 days, complete neurologic recovery, defined as CPC 1 at discharge, was associated with better long-term survival compared with neurologic disabilities at the same time point.

Study context

Population
Adults who survived in-hospital cardiac arrest (IHCA) or out-of-hospital cardiac arrest (OHCA) beyond 30 days with Cerebral Performance Category (CPC) assessment at hospital discharge, Sweden, 2010–2019
Participants
9,390 cardiac arrest survivors
Exposure
CPC 2 or CPC 3-4 vs CPC 1 at hospital discharge
  • CPC 1n = 7,374reference
  • CPC 2n = 1,358
  • CPC 3-4n = 658
Outcome
Long-term survival
Methodological detailsnationwide registry-based, 4 mandatory national registers
  • Nationwide registry-based
  • 4 mandatory national registers

Main finding

As reported in the abstract

5 years
Each group vs CPC 1AHR for death (95% CI)
CPC 2
1.57(1.40–1.75)
CPC 3-4
2.46(2.13–2.85)

Observational data: associations, not effects.

Further findings

Long-term survival, OHCA and IHCA (subgroup)

Similar associations in the OHCA and IHCA groups

Original publication

Neurologic Recovery at Discharge and Long-Term Survival After Cardiac Arrest. JAMA Netw Open. Published 1 October 2024. doi:10.1001/jamanetworkopen.2024.39196

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