Neurological outcomes 30 days after cesarean delivery under spinal anesthesia in women with moyamoya disease: A single-center retrospective case-control study (2005–2021)
Main finding · Stroke or transient ischemic attack (delivery level)Result — go to the resultCrude odds ratio 235.7 95% CI 29.3–1892.2Authors' conclusion
Moyamoya disease was associated with early neurological events after cesarean delivery under spinal or combined spinal epidural anesthesia; this association does not imply causality
Study context
- Population
- Cesarean deliveries under spinal or combined spinal epidural anesthesia, single center, 2005–20211,910 screened
- Participants
- 1,750 participants
- Comparison
- Moyamoya disease vs no moyamoya disease
- Moyamoya diseasen = 73
- No moyamoya diseasen = 1,677reference
- Outcome
- Confirmed stroke or transient ischemic attack
- Follow-up
- 30 days
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Crude odds ratio
235.7
95% CI 29.3–1892.2
P < 0.001
Events by group
Observational data: associations, not effects.
Secondary outcomes
Any neurological diagnosis or symptom (delivery level) · 30 days
- Moyamoya disease vs no moyamoya disease
- 31/73 (42.5%) vs 214/1677 (12.8%)
Any neurological diagnosis or symptom excluding PDPH (sensitivity analysis) · 30 days
- Moyamoya disease vs no moyamoya disease
- 25/73 (34.2%) vs 207/1677 (12.3%)
- Sensitivity analysis
Stroke or TIA (woman-level sensitivity analysis, index cesarean delivery) · 30 days
- Moyamoya disease vs no moyamoya disease
- 8/48 (16.7%) vs 1/1,445 (0.07%)
- All events occurred within 7 days
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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