Pediatric anesthesia & critical care
Neuromuscular Monitoring of Rocuronium 0.6 mg/kg in Children Aged 3–24 Months With Electromyography and Acceleromyography: An Observational Study
Authors' conclusion
Time to TOFR ≥ 0.9 after rocuronium 0.6 mg/kg in children aged 3-24 months was significantly shorter with AMG compared to EMG at both the UN and TN.
Study context
- Population
- Children aged 3–24 months scheduled for elective surgery under GA with rocuronium 0.6 mg/kg
- Participants
- 107 children
- Exposure
- Acceleromyography (AMG) vs electromyography (EMG) train-of-four (TOF) monitoring at the tibial nerve (TN) and the ulnar nerve (UN)
- TNn = 50
- UNn = 50
- Outcome
- Time to train-of-four ratio (TOFR) ≥ 0.9
Main finding
As reported in the abstract
Mean difference, min (95% CI)P value
TN, EMG vs TN, AMG
34(29–39)
P < 0.0001UN, EMG vs UN, AMG
11(6–15)
P < 0.0001Observational data: associations, not effects.
Safety
- Patients with symptoms of residual neuromuscular block
- 17
Original publication
Neuromuscular Monitoring of Rocuronium 0.6 mg/kg in Children Aged 3–24 Months With Electromyography and Acceleromyography: An Observational Study. Paediatr Anaesth. Published 19 May 2026. doi:10. 1002/ pan. 70220
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