Cardiac arrest & resuscitation
Neuroprognostication in Extracorporeal Membrane Oxygenation Patients After Cardiac Arrest: A Narrative Review
Authors' conclusion
Although neuroprognostication in ECMO patients is uncertain and difficult, available instruments may provide key prognostic information when used with appropriate caution and by expert interpreters.
Study context
- Population
- Extracorporeal membrane oxygenation (ECMO)-supported patients following cardiac arrest
- Outcome
- Accuracy of neuroprognostic tools in ECMO patients after cardiac arrest
Methodological detailsnarrative systematic review, literature 2014–2024
- Narrative systematic review
- Literature 2014–2024
Pooled result
As reported in the abstract
- Traditional neuroprognostic tools perform reasonably well in ECMO patients, with caveats
- Neuron-specific enolase increased by hemolysis
- EEG and evoked potentials unreliable
- MRI contraindicated
- Multimodal approach with at least two criteria for poor outcome seems justified in ECMO and non-ECMO populations
Original publication
Neuroprognostication in Extracorporeal Membrane Oxygenation Patients After Cardiac Arrest: A Narrative Review. J Cardiothorac Vasc Anesth. Published 27 October 2025. doi:10. 1053/ j. jvca. 2025. 10. 011
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