Perioperative medicine & outcomes
Non-fasting versus fasting before percutaneous cardiac procedures: a systematic review and meta-analysis of randomized controlled trials
Authors' conclusion
The non-fasting protocol demonstrated comparable efficacy, safety, and overall satisfaction to the conventional fasting approach.
Study context
- Population
- Patients undergoing percutaneous cardiac procedures
- Participants
- 2,034 patients · 5 RCTs
- Comparison
- Non-fasting vs fasting before percutaneous cardiac procedures
Pooled result
As reported in the abstract
- No significant difference between groups in patient satisfaction, aspiration, pneumonia, emergency intubation, nausea/vomiting, anti-emetic use, hypoglycemia or inotrope/vasopressor need; tiredness/fatigue significantly decreased with non-fasting
Further pooled results
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Anti-emetic use | 0.49 (0.24–1.03) | P = 0.06 | |
| 0.20.5125Relative risk (log scale) |
| Outcome | SMD (95% CI) | P value |
|---|---|---|
| Patient satisfaction score | - 0.65 (- 1.39, 0.09) | P = 0.08 |
| Sensation of tiredness/fatigueSignificantly decreased with non-fasting | - 0.31 (- 0.51, - 0.11) | P < 0.001 |
Safety
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Intra/postoperative aspiration | 1.00 (0.20–4.96) | P = 1.00 | |
| Postprocedural pneumonia | 0.60 (0.14–2.51) | P = 0.49 | |
| Emergency endotracheal intubation | 0.99 (0.10–9.51) | P = 1.00 | |
| Nausea/vomiting | 0.89 (0.46–1.76) | P = 0.75 | |
| Hypoglycemia | 0.74 (0.43–1.28) | P = 0.28 | |
| Need for inotrope/vasopressor therapy | 1.03 (0.81–1.30) | P = 0.82 | |
| 0.10.31310Relative risk (log scale) |
Original publication
Non-fasting versus fasting before percutaneous cardiac procedures: a systematic review and meta-analysis of randomized controlled trials. Perioper Med (Lond). Published 28 February 2025. doi:10.
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