Pediatric anesthesia & critical care

Non‐Intubated Spontaneous Ventilation Versus Endotracheal Intubation Anesthesia for Pediatric Thoracoscopic Lung Resection: A Retrospective Propensity‐Score‐Matched Study

Paediatr AnaesthPublished Retrospective cohort study

Authors' conclusion

In this retrospective propensity-score-matched pediatric cohort, a laryngeal mask airway-assisted non-intubated spontaneous ventilation anesthesia was feasible and was not associated with worse perioperative outcomes than a conventional endotracheal intubation anesthesia. A lower observed incidence of postoperative pulmonary complications was noted.

Study context

Population
Children undergoing thoracoscopic anatomical lung lesion resection for pulmonary sequestration or congenital pulmonary airway malformation, April 2024–May 202550 matched pairs analysed
Participants
198 children
Exposure
Non-intubated spontaneous ventilation vs Endotracheal intubation
  • Non-intubated spontaneous ventilationn = 50
  • Endotracheal intubationn = 50reference
Outcome
Overall incidence of PPCs before discharge
Follow-up
Before discharge
Methodological detailssingle-centre, propensity-score matched
  • Single-centre
  • Propensity-score matched

Main finding

As reported in the abstract

Absolute risk reduction

12.0 %

95% CI 3.0–21.0

P = 0.027

Events by group

Observational data: associations, not effects.

Secondary outcomes

OutcomeaOR (95% CI)P value
PPCs, sensitivity analysis (Firth's logistic regression adjusted for thoracic paravertebral block)0.06 (0.0004–0.76)P = 0.029
OutcomeNon-intubated spontaneous ventilation
Conversion to endotracheal intubation0 events

Other secondary outcomes (lowest SpO2, highest end-tidal CO2, PACU LOS, chest tube time, postoperative hospital LOS)

Modest between-group differences in unadjusted analyses; Holm-Bonferroni adjusted p values
0.060 to 0.208
  • Holm-Bonferroni adjustment

Original publication

Non‐Intubated Spontaneous Ventilation Versus Endotracheal Intubation Anesthesia for Pediatric Thoracoscopic Lung Resection: A Retrospective Propensity‐Score‐Matched Study. Paediatr Anaesth. Published 13 March 2026. doi:10.1002/pan.70160

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