Pain medicine

Non-neurodestructive ganglion impar blocks for coccydynia and related disorders: a systematic review and meta-analysis

Reg Anesth Pain MedPublished Systematic review and meta-analysis

Authors' conclusion

Non-neurodestructive GIB may be a safe and potentially effective treatment option for patients with chronic, refractory coccydynia.

Study context

Population
Patients with chronic coccydynia
Participants
625 patients · 17 studies
Comparison
Pain before vs after non-neurodestructive ganglion impar block
  • GIBn = 625
Outcome
Coccygeal pain (VAS or NRS, 0 to 10), change from baseline
Methodological detailsPRISMA, GRADE assessment
  • PRISMA
  • GRADE assessment

Pooled result

As reported in the abstract

Coccygeal pain vs baseline (meta-analysis, 11 studies, 391 patients; baseline pain 7.93, 95% CI 7.81 to 8.04)
GIBSMD (95% CI)
Short-term (up to 3 months)
−2.73(−3.45 to −2.01)
Intermediate-term (3-6 months)
−2.13(−2.82 to −1.45)
Long-term (>6 months)
−1.86(−2.58 to −1.15)

Safety

No serious adverse events were noted

Original publication

Non-neurodestructive ganglion impar blocks for coccydynia and related disorders: a systematic review and meta-analysis. Reg Anesth Pain Med. Published 12 March 2025. doi:10.1136/rapm-2024-106055

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