Pain medicine

Nonopioid Analgesic Prescriptions Filled after Surgery among Older Adults in Ontario, Canada: A Population-based Cohort Study

AnesthesiologyPublished Population-based cohort study

Authors' conclusion

The proportion of postoperative patients who fill prescriptions for nonopioid analgesics has increased.

Study context

Population
Adults aged 66 yr or older undergoing surgery in Ontario, Canada, fiscal years 2013–2019
Participants
278,366 admissions
Exposure
Nonopioid analgesic prescriptions filled after surgery, 2013 vs 2019
Outcome
Percentage of patients with new filled prescriptions for nonopioid analgesics
Follow-up
Within 7 days of discharge
Methodological detailslinked health administrative data
  • Linked health administrative data

Main finding

As reported in the abstract

Filled nonopioid prescription within 7 days postoperatively

Observational data: associations, not effects.

Secondary outcomes

Acetaminophen prescription filled · greatest increase

Combination analgesic prescription filled

Both separate opioid and nonopioid prescriptions filled

Overall received both an opioid and a nonopioid

Overall received both an opioid and a nonopioid

Remained constant over time

Analgesic class filled, overall

No opioid prescription
22% (n = 60,181)
Nonopioid only
2% (n = 5,534)
Opioid only
21% (n = 59,608)
Some combination of opioid and nonopioid
55% (n = 153,043)

Original publication

Nonopioid Analgesic Prescriptions Filled after Surgery among Older Adults in Ontario, Canada: A Population-based Cohort Study. Anesthesiology. Published 21 November 2022. doi:10.1097/aln.0000000000004443

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