Pain medicine

Nonpharmacological Adjuncts to Reduce Perioperative Anxiety and Pain for Awake Gynecological Procedures: A Scoping Review

Anesth AnalgPublished Scoping review

Authors' conclusion

Overall, although many nonpharmacological interventions appear promising in managing perioperative anxiety and pain across diverse gynecological procedures, VR and music therapy demonstrated particular promise given their consistent patterns in reducing anxiety and pain, as well as scalability and feasibility.

Study context

Population
Patients undergoing awake gynecological procedures91 studies · 105 interventions
Comparison
Nonpharmacological adjuncts vs standard care or comparators
Outcome
Pain and anxiety across interventions
Methodological detailsOvid MEDLINE, Embase, SCOPUS, Cochrane CENTRAL, and Google Scholar searched from inception to December 3, 2024
  • Ovid MEDLINE, Embase, SCOPUS, Cochrane CENTRAL, and Google Scholar searched from inception to December 3, 2024

Main finding

As reported in the abstract

Interventions assessing pain

84/105, 80.0%

Reported reductions in pain

65.5%

55/84

Interventions assessing anxiety

72/105, 68.6%

Reported reductions in anxiety relative to controls or baseline

66.7%

48/72

Further findings

Intervention types

Unique intervention types
19
Virtual reality (VR)
22/105, 21.0%
Music therapy
17/105, 16.2%
Acupuncture
12/105, 11.4%

Study characteristics

Therapeutic and diagnostic procedures (eg, hysteroscopies)
33/91, 36.3%
RCTs
63/91, 69.2%
Compared with standard care
78/105, 74.3%

Feasibility

Generally feasible; acceptability and satisfaction comparable to standard of care or comparators

Original publication

Nonpharmacological Adjuncts to Reduce Perioperative Anxiety and Pain for Awake Gynecological Procedures: A Scoping Review. Anesth Analg. Published 10 August 2026. doi:10.1213/ane.0000000000008216

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