Oblique subcostal transverse abdominis plane block for postoperative pain control in patients undergoing open sublay mesh hernia repair: a prospective double-blind randomized placebo-controlled clinical trial
Authors' conclusion
Bilateral oblique subcostal transverse abdominis plane blocks in patients undergoing sublay mesh hernia repair were not associated with a prolonged reduction in patient-controlled total morphine consumption in the evening of the second POD in this study.
Study context
- Population
- Patients scheduled for open sublay mesh hernia repair
- Participants
- 19 vs 17
- Comparison
- Ropivacaine vs Placebo
- Ropivacainen = 19
- Placebon = 17reference
- Primary endpoint
- Patient-controlled total morphine consumption
- Follow-up
- 8:00 p.m. on POD 2
Methodological detailssingle-centre, prospective, placebo-controlled, double-blind
- Single-centre
- Prospective
- Placebo-controlled
- Double-blind
Primary result
As reported in the abstract
Total morphine consumption
P = 0.04
Secondary outcomes
Morphine consumption from 8:00 p.m. on the first POD until 8:00 a.m. on the second POD
P = 0.01
| Outcome | Ropivacaine | Placebo | P value |
|---|---|---|---|
| Total morphine consumption during PACU stay | median 4 (IQR 4–9) mg | — not stated in the abstract | P = 0.04 |
| Maximum pain score since last assessment · 8:00 a.m. on the second PODMedian | 5 (IQR 4–7) | 4 (IQR 3–5) | P = 0.03 |
— not stated in the abstract
Total morphine consumption during PACU stay
- Abstract states ropivacaine received 2 mg less morphine during PACU stay
Safety
- No differences in adverse events between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Oblique subcostal transverse abdominis plane block for postoperative pain control in patients undergoing open sublay mesh hernia repair: a prospective double-blind randomized placebo-controlled clinical trial. Reg Anesth Pain Med. Published 8 July 2024. doi:10.
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