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Obstructive Sleep Apnea Among Gravidas With Chronic Hypertension Compared to Matched Controls: A Prospective Cohort Study
Authors' conclusion
cHTN and age are important risk factors for OSA in gravidas.
Study context
- Population
- Adult gravidas at 10–20 weeks of gestation, with and without chronic hypertensioncompleted home sleep test ≥2 h
- Participants
- 100 participants
- Exposure
- Chronic hypertension vs normotensive gravidas
- Chronic hypertension (cHTN)n = 50
- Normotensiven = 50reference
- Outcome
- Obstructive sleep apnea (OSA) prevalence in gravidas with cHTN vs normotensive gravidas matched for BMI and gestational age
Methodological detailssingle-centre, body mass index (BMI) matched
- Single-centre
- BMI matched
Main finding
As reported in the abstract
OSA prevalence
cHTN vs NormotensiveEstimate (95% CI)P value
Prevalence difference P = .009
OR 2.90(1.30–6.65)
P = 0.01Adjusted for age; no overall association
aOR 2.22(0.92–5.40)
P = 0.076Observational data: associations, not effects.
Secondary outcomes
Moderate or severe OSA
P = 0.009
| Outcome | aOR (95% CI) | P value | |
|---|---|---|---|
| OSA (subgroup: gravidas older than 25 years) | 2.64 (1.06–6.71) | P = 0.038 | |
| 0.10.31310Adjusted odds ratio (log scale) |
Age
P < 0.001
Original publication
Obstructive Sleep Apnea Among Gravidas With Chronic Hypertension Compared to Matched Controls: A Prospective Cohort Study. Anesth Analg. Published 10 November 2022. doi:10.
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